Genomic Medicine and Statistics

University of Oxford has opted into the TEF and received a Gold award.

The information provided on this page was correct at the time of publication (October 2020). For complete and up-to-date information about this course, please visit the relevant University of Oxford course page via www.graduate.ox.ac.uk/ucasThis four-year DPhil programme aims to train and nurture future leaders in the application of genomics to advance human health, equipping them with skill sets spanning experimental and analytical genomic science in order to realise the potential of genomics and practice the qualities of fair and inspiring leadership that we will instil during the course.The first year includes taught modules focused within the first term. First-year students then undertake short research projects in up to three laboratories in three-month rotations, with further training and teaching sessions tailored to the needs of individual students. The research projects and lab visits help inform the choice of DPhil project to be undertaken over the subsequent three years of the programme. The final three years of the course will comprise doctoral research under the supervision of two named supervisors and a doctoral committee. Applicants are advised to visit the Doctoral Training Centre course webpage for further information about supervisors connected to this programme.The programme actively seeks to recruit students from very diverse backgrounds, ranging from genetics to pure maths but united by a track record of academic excellence and enthusiasm for this field. Students receive world-class training, supervision, mentorship and pastoral support. Promoting excellence in research culture underlies all aspects of the programme with a commitment to support creativity, prioritise diversity and inclusion, and promote best practice.Module informationThe programme is focused on the following themes:

• genomic and -omic technologies (including method development, single cell genomics, imaging, model systems, CRISPR screens, genome engineering, proteomics, metabolomics, high throughput screening)
• functional genomics (gene regulation and epigenetics)
• genome biology (genetic variation, recombination, human history, evolution, palaeogenomics, pathogen genomes)
• genomics of disease (Mendelian, multifactorial traits, cancer)
• genomic analysis (bioinformatics and statistical genetics)

from genes to clinical proof of concept (integrated drug development pipeline spanning genetic-led target discovery, structural biology, medicinal chemistry)

• application of genomics in the clinic (rare disease diagnostics, cancer therapeutics, personalised medicine and genome therapies).

Teaching modules combine theoretical and practical classes, with further skills training available through the Medical Sciences Doctoral Training Centre.Teaching and learningThe taught component of the course will be delivered by expert faculty including experienced principal investigators and postdoctoral scientists. Class sizes for taught modules will typically be between 5 and 20 students depending on format and content (median estimated at 12 students). Peer-to-peer and independent learning is also encouraged. Lab rotations will be under the supervision of a named principal investigator. Workload involved is commensurate with full time employment.

Some 140 countries have attendees at Oxford and some 60% of the total student body is from outside the UK. There are various programs available for international students to help with orientation and integrating with life in Oxford as well as to help with legal matters such as immigration and visas. They can also help with practical matters such as dealing with finances and accessing health care with the National Health Service (NHS). Student life is filled with many traditions as befits a university of Oxford's age. One of these are the balls, held by the colleges with a formal dress code as well as smaller events regularly during the year. The Oxford University Student Union or OUSU, represents students and is their voice in debate about the university as well as organising student life organisations. There are a large number of sports available outside the classroom and many of these are of a high standard. The Boat Race is a famous example of a rowing race with nearby Cambridge University that is watched by up to 10 million TV viewers each year. There are also student newspapers and a radio station as well as performing arts groups. There are also student societies open to students who aren't studying the subject to learn something new and different.

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